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The DNA-binding protein inhibitors Id2 and Id4 showed decreased expression during OPC differentiation in mice, which was correlated with hypermethylation of their promoter regions, suggesting a role for DNA methylation in the silencing of these genes to allow the expression of myelin genes during differentiation [104]

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4), and presents a potential therapeutic target for the prevention of organ I/R damage, e.g., solid organ transplantation

Solubilization and purification of enzymatically active glutathione s-transferase (pGEX) fusion proteins

ZnT8 loss-of-function accelerates functional maturation of hESC-derived beta cells and resists metabolic stress in diabetes

Hum Reprod (2013) 28(11):293042