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Diabetes promotes raised mitochondrial damage and ROS production to retinal microvessels, leading to corresponding inflammation and oxidative stress which induces DR

In addition, both Sev and ketamine led to the upregulation of RASD1, which can form a ternary complex with DMT1 and PAP7, thereby enhancing the capability of NMDARs to activate DMT1 for iron uptake (White et al., 2016), causing iron-induced cellular damage

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MSCs can inhibit DC differentiation, maturation, and antigen-presenting functions, thereby disrupting the secretion of proinflammatory cytokines

Supplementary material The Supplementary Material for this article can be found online at: References 1 AndradeM