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Hyperlysinemia: An ultrarare inborn error of metabolism-Review and case update

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Agents Actions 43 , 8690 (1994)

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DSIP (delta sleep-inducing peptide) was first isolated from rabbit cerebral venous blood in 1974 and has accumulated a small but published clinical-trial base most notably a 1992 Schneider-Helmert study showing improved sleep with DSIP infusion in chronic insomniacs over 7 successive nights and earlier studies showing improved sleep duration in middle-aged chronic insomniacs

We highlight recent findings on the cellular and molecular mechanisms driving ferroptosis, its impact on tissue remodeling, and potential therapeutic opportunities