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Therefore, this study is pioneering in evaluating the brain targeting of BER through intranasal delivery of chitosomes via the olfactory mucosa for PD management

Targeting GPR30 with G-1: a new therapeutic target for castration-resistant prostate cancer

4 Limitations and countermeasures of curcumin in clinical application 4.1 Limitations of curcumin application However, the application of curcumin is limited by its physicochemical properties, particularly its low water solubility and poor intestinal permeability

doi: 10.1017/S0007114509359127 125

Glutathione plays a crucial part in neutralising harmful free radicals, reducing oxidative stress, and aiding the bodys detoxification processes, all of which contribute to healthier skin

Moreover, oxidative stress appears to provide a critical link between environmental factors such as exposure to pesticides, herbicides, and heavy metals with endogenous and genetic risk factors in the pathogenic mechanisms of neurodegeneration, particularly in Parkinsons disease (63, 608, 632)