Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan deuterium-labeled-ether Molecular Weight Cannot read molecule

Molecular Weight Cannot read molecule file

Product Name tert-butyl 2-[4-(2-aminoethyl)piperazin-1-yl]acetate Synonyms CAS Number n/a Related CAS Molecular Formula C12H25N3O2 Molecular Weight 243

S)-AHPC-CO-C6-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C33H52Cl2N6O4S Molecular Weight 699

418 SMILES OC(=O)CCN1CCN(CC1)C1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) 95% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only

Product Name Thalidomide-O-acetamido-PEG5-C2-azide Synonyms Thalidomide-4'-O-acetamido-PEG5-C2-azide CAS Number n/a Related CAS Molecular Formula C27H36N6O11 Molecular Weight 620

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan deuterium-labeled-ether Molecular Weight Cannot read moleculeSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I