(S,R,S)-AHPC-CO-PEG7-propargyl deuterium-labeled-amine 167 SMILES [2H]C([2H])([2H])OC1=CC=C(C=C1)C(O)=O Purity (HPLC)

167 SMILES [2H]C([2H])([2H])OC1=CC=C(C=C1)C(O)=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

38 SMILES Cl

96 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCCOCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

339 SMILES OCCCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

the components of the reaction are bioinert

(S,R,S)-AHPC-CO-PEG7-propargyl deuterium-labeled-amine 167 SMILES [2H]C([2H])([2H])OC1=CC=C(C=C1)C(O)=O Purity (HPLC)Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name (S,R,S) AHPC CO PEG7 propargyl Synonyms CAS Number n a Related CAS Molecular Formula C40H60N4O11S Molecular Weight 805 SMILES