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These results suggest that crocodilian oil may exert antifibrotic effects by modulating the TGF-1/Smad3 pathway, thereby improving scar outcomes (see Figure 5)

3.2.1 Limitations of current AD treatments and the need for new approaches Despite continuous advancements in AD drug development, currently available treatments do not effectively halt or reverse disease progression

Covalent binding of 2-phenylpropionyl-S-acyl-CoA thioester to tissue proteins in vitro