Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-MMAE Size:1mg making the linkers highly adaptable

making the linkers highly adaptable for diverse ADC and related applications

Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C48H73N11O19 Molecular Weight 1108

836 SMILES: [O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCCOCCOCCOCC#C Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

823 Purity (HPLC) >= 95% Solubility DMSO

Product Name Pomalidomide-5'-PEG5-OH Synonyms CAS Number 2641838-56-2 Related CAS Molecular Formula C23H31N3O9 Molecular Weight 493

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-MMAE Size:1mg making the linkers highly adaptableSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly