Trametinib Size:5mg 82 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCO)C(C)(C)C)C=C1 Purity (HPLC)

82 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCO)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

OC(=O)C(F)(F)F

28 SMILES: CC(=O)OC1=C(Cl)C=C2C(OC3=CC(OC(C)=O)=C(Cl)C=C3C22OC(=O)C3=CC(=CC=C23)C(O)=O)=C1

such as trans-cyclooctene (TCO) or norbornene derivatives

Product Name Phthalimidinoglutarimide-5'-propargyl-PEG2-OH Synonyms CAS Number n/a Related CAS Molecular Formula C20H22N2O6 Molecular Weight 386

Trametinib Size:5mg 82 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCO)C(C)(C)C)C=C1 Purity (HPLC)Trametinib (GSK1120212; JTP 74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib binds KRS MEK and disrupts RAF MEK. Product Name Trametinib Synonyms CAS Number 871700 17 3 Related CAS Molecular Formula C26H23FIN5O4 Molecular Weight 615. 404 SMILES CN1C(=O)C(C)=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC1=C(F)C=C(I)C=C1)C1=CC(NC(C)=O)=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO, DMF