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The more common cause of TP reduction is the decrease in ALB, which is the major protein component of serum TP, playing a role in maintaining plasma osmotic pressure and transporting nutrients (37)

The vitamin is found in meat, fish, eggs and dairy, but very little is contained in plants

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Preclinical studies have shown that cobalamin inhibits glutamate exocytosis, as an excitatory pain neurotransmitter, and when infused intracerebroventricularly, increases GABA cell contents, as an inhibitory pain neurotransmitter [6, 9]

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