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Alpha-lipoic acid in diabetic peripheral neuropathy: addressing the challenges and complexities surrounding a 70-year-old compound

157 The KD is a biochemical model of fasting or starvation, which promotes the utilization of KBs as the dominant fuel source to replace glucose in the central nervous system

The clathrin-coated pits are endocytosed into the cell, together with PCSK9, a proprotein convertase that marks the LDL receptor for degradation, and are delivered to the endosomes as vesicles with their cargo of proteinss and LDL

Finally, radiological and clinical follow-ups in patients diagnosed with malignant melanotic nerve sheath tumors are important, given the median time to recurrence or metastasis of around 2 years, with some patients experiencing deterioration as late as 10 years postoperatively

Nocturnal awakenings and difficulty resuming sleep: their burden in the European general population

249 Interventions such as light therapy, sleep improvement strategies, and melatonin supplementation can help regulate circadian rhythms, potentially benefiting diabetes management and reducing complications, including DR