DBCO-Lys(m-PEG4)-Val-Cit-PAB Size:25mg As a negative control

As a negative control

06 Purity (HPLC) >= 95% Physical Appearance Light Yellow Solid Optical Properties n/a Solubility DMSO

1038/s41586-020-2760-4

TCO (trans-cyclooctene) is a strained alkene used in click chemistry for bioorthogonal reactions like iEDDA (inverse electron-demand Diels-Alder)

Product Name Pomalidomide-5'-PEG3-C2-amine HCl Synonyms CAS Number n/a Related CAS 1957236-37-1 (free base) Molecular Formula C21H29ClN4O7 Molecular Weight 484

DBCO-Lys(m-PEG4)-Val-Cit-PAB Size:25mg As a negative controlSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,