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IFN also induces an increase in barrier permeability through the reduction of ZO-1 and occludin expression in an adenosine monophosphate-activated protein kinase (AMPK)-dependent pathway, irrespective of the cellular energy levels 62

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[22] [18] Pseudovitamin B 12 is the majority corrinoid in spirulina, an algal dietary supplement sometimes erroneously claimed as having this vitamin activity