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Because there is inherently some variability between apparatus, the current practice introduces a potential confound for comparing results across institutions, labs and studies

Posttranslational modifications affect the interaction of S100 proteins with tumor suppressor p53

Long noncoding RNA Pvt1 promotes the proliferation and migration of Schwann cells by sponging microRNA-214 and targeting c-Jun following peripheral nerve injury

140), while additionally reporting additional beneficial effects on cytotoxic oxidative stress (Steckert et al., 2012)

To reduce the risk of overfitting the algorithm, we train and test in a 5-fold cross validation on 80% of the available data, leaving 20% as an internal validation cohort

Fotherby MD, Williams JC, Forster LA, Craner P, Ferns GA