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Based on the coefficient of determination (R 2 = 58.2) it means that 66.1% of the severity of melasma is influenced by plasma GSH levels, the remaining 33.9% is influenced by other factors

doi: 10.1002/mco2.104 92

Whereas 2-OBA requires esterification for cellular uptake, 2-AB is incorporated directly into cells, followed by an increase in intracellular GSH levels