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finds that inhibition of SLC7A11 after Erastin treatment increases radiosensitivity in SLC7A11 + breast cancer cells in vitro and in vivo , while it has no effect on SLC7A11 - cancer cells, this process accompanied by a decrease in intracellular GSH synthesis that promotes cell death (Ye et al., 2020)

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10.1038/s41586-020-2309-6 54 FergusonR.GooldR.CouplandL.FlowerM.TabriziS

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Some studies suggest that higher doses, up to 2,000 mg per day , may be beneficial for specific conditions, such as chronic illness or high oxidative stress

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