Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg 644 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC)

644 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name tert-butyl 4-[2-(piperazin-1-yl)ethyl]piperazine-1-carboxylate Synonyms CAS Number 164332-19-8 Related CAS Molecular Formula C15H30N4O2 Molecular Weight 298

Compared to the original Cy5 dye

Product Name 1-bromo-4-(methoxy-d3)benzene Synonyms 1-bromo-4-(²H3)methoxybenzene CAS Number 100835-59-4 Related CAS Molecular Formula C7H7BrO Molecular Weight 190

48 Purity (HPLC) >= 95% Physical Appearance Dark Blue Solid Optical Properties Abs/Em Maxima: 650/660nm Solubility DMSO

Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg 644 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The