Fmoc-Val-Cit-PAB dsa Product Name DOTA-tris(t-Bu)ester-PEG4-propargyl Synonyms CAS

Product Name DOTA-tris(t-Bu)ester-PEG4-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C39H71N5O11 Molecular Weight 786

918 Purity (HPLC) >= 95% Solubility DMSO

S)-AHPC-CO-PEG2-C2-amine HCl Synonyms CAS Number 2138439-54-8 Related CAS Molecular Formula C29H44ClN5O6S Molecular Weight 626

10-tetraacetic acid) consists of a 12-membered tetraaza ring (cyclen) with four nitrogen atoms

345 SMILES OCCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Fmoc-Val-Cit-PAB dsa Product Name DOTA-tris(t-Bu)ester-PEG4-propargyl Synonyms CASFmoc Val Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug, and the Fmoc protecting group can be removed to enable further functionalization or conjugation. Product Name Fmoc Val Cit PAB Synonyms Fmoc VC PAB OH CAS Number 159858 22 7