Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Sulforhodamine B 557 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC)

557 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

SulfoCy3(Sulfo-Cyanine3

01 SMILES CNC(=O)COC1=CC2=C(C=CC(=C2)N(C)C2=NC(=NC=C2Cl)N2C[C@@H](C)C[C@@H](C)C2)N(C)C1=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

178 Purity (HPLC) >= 95% Solubility DMSO

the components of the reaction are bioinert

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Sulforhodamine B 557 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para