DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg This probe is also ef

This probe is also ef

Datasheet          MSDS

and cell permeability

59 SMILES Cl

NCCOCCN1CCN(CC1)C1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) 95% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only

DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg This probe is also efSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing