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Additionally, the synthetic capsaicin analog Arvanil induces high mitochondrial calcium flux, opening the mitochondrial membrane permeability transition pore (mPTP) and triggering ferroptosis in hepatocellular carcinoma (70)

This can lead to improved endurance, increased energy levels, and decreased muscle fatigue (5)

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Here, we report the development of a new viologen-based redox cycling agent, mito-diquat (Mito-DQ), capable of inducing targeted mitochondrial O 2 production at significantly higher rates as compared to previously reported mito-paraquat (Mito-PQ), a widely used chemical tool to study mitochondria-dependent redox signaling

Recently, selectively-targeting liposomes were constructed that were able to accurately deliver their contents to a specific organ such as the liver, lung, and spleen (162)

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