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Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4) tamra S)-AHPC-acetamido-O-PEG3-C2-azide Synonyms CAS Number 1797406-81-5

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4) tamra S)-AHPC-acetamido-O-PEG3-C2-azide Synonyms CAS Number 1797406-81-5SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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Description

S)-AHPC-acetamido-O-PEG3-C2-azide Synonyms CAS Number 1797406-81-5 Related CAS Molecular Formula C32H47N7O8S Molecular Weight 689

NCCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

599 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCOCCOCCOCCOCCOCCOCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-CO-PEG4-C2-acid Synonyms CAS Number 2172820-12-9 Related CAS Molecular Formula C34H50N4O10S Molecular Weight 706

Product Name Azide-Propionyl-Val-Cit-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C39H67N9O14 Molecular Weight 886

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4) tamra S)-AHPC-acetamido-O-PEG3-C2-azide Synonyms CAS Number 1797406-81-5SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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