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Data Availability Statement All relevant data are contained in this manuscript.

Molecular Mechanism: Phenylephrine functions as a selective $\alpha_1$-adrenergic receptor agonist

While the origin is unknown, the connection between creatine supplementation and kidney damage/renal dysfunction could be traced back to two things: a poor understanding of creatine and creatinine metabolism and a case study published in 1998. Original study CREATINE

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