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Int J Vitam Nutr Res 2010;80:330-5

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Those with diseases that affect the gut, such as Crohns disease or celiac disease, are also at risk ( Summary Those at greatest risk of vitamin B12 deficiency are vegans and vegetarians, who get little to no B12 from the diet

That said, for milder hangovers without severe symptoms, good old-fashioned oral hydration and appropriate over-the-counter medications will likely do the trick at a fraction of the cost