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Many studies have also shown that human and mouse cells also have ample supplies of cytochrome p450, which further converts NNN and NNK into compounds such as formaldehyde and methyldiazohydroxide that can react with DNA to form damaging adducts such as gamma-hydroxy-propanodeoxyguanosine and O6-methyl-deoxyguanosine, the researchers say

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To view a copy of this license, visit About this article Cite this article Gunnerbeck, A., Lundholm, C., Rhedin, S

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The spotlighted research was funded by the National Institutes of Health, the FDA Center for Tobacco Products, and the UCSF Cancer Center