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PREPs were defined as products that substantially reduce exposure to one or more tobacco smoke toxicants as compared to exposures resulting from traditional tobacco products, and, that as a result, might be reasonably expected to reduce the risk of one or more specific diseases or other adverse health effects as compared to the risks associated with use of traditional tobacco products

It may also lead to an elevation in free fatty acids and oxidative stress and DNA damage [51]

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There is evidence this happened across the Bay, at a Westmoreland County site (44WM12)

The review's evidence supports the superior efficacy of regenerative treatments, although conventional methods continue to be prevalently employed

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