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Treatment Resistant Schizophrenia: Effects of Smoking on Clozapine and Health Page 2 of 3 Psychiatry Advisor The Intrinsic Receptor Deficit In the general population, chronic smoking leads to an upregulation of 42 nicotinic receptors. In schizophrenia, this compensatory upregulation is impaired. This suggests an intrinsic defect in the Nicotine Dependence and Schizophrenia ScienceDirect The Effects of Nicotine & Caffeine on People Who Have Schizophrenia Tobacco and schizophrenia: National Elf Service Smoking linked with schizophrenia Health News The Indian Express
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