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2 Yinghua East Street, Chaoyang District, Beijing, 100029, Peoples Republic of China, Email [email protected] Abstract: Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous respiratory disorder that arises from interactions between genetic susceptibility and environmental exposures, with cigarette smoking being the primary modifiable risk factor

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In another study, nearly 1,000 rats were killed in a study in which most were forced to breathe either diesel engine exhaust or cigarette smoke for 6 hours a day, 7 days a week for two years to compare the effects of exposure on their lungs

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