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Nicotine, the main active ingredient in tobacco, initially acts as a stimulant by triggering the release of adrenaline and dopamine, which: Increase heart rate Raise blood pressure Stimulate brain activity This is why smokers often experience an initial rush or sense of alertness and pleasure after using tobacco

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8 Weird Facts You Never Knew About Your Heart: The findings of this study suggest that simply limiting your cigarettes isnt the answer

But the latest subvariant, BA.5, could be reversing that trend