The earliest records of use in Europe and Islam are 1190 CE
Aerosols were drawn into a 60-mL syringe and then delivered into the trachea only during inspiration, at a frequency of 20 breaths/min and a tidal volume of 500 mL, via the inspiration tubing of a piston respirator
Home test kits can also be used
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These ultrafine particles can reach deep into the lungs, including the smallest airways, called bronchioles
