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The issue also remains that Korean smokers who vape have been shown to initiate smoking earlier than non-vapers and earlier initiation of smoking dramatically increases lung cancer risk - after controlling for pack years ( Given several other issues, including the possibility of reverse causation, doubts remain whether the conclusions reliably reflect the data

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It is also important to note that some e-liquids contain other potentially harmful chemicals, such as formaldehyde, which can cause respiratory problems if inhaled in large amounts