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How e-cig use will affect developing adolescent brains as well as long-term health impacts are unknown

Most online cigarette retailers sell cigarettes in cartons

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For example, in a discordant twin study, unaffected co-twins had higher smoking rates and poorer quit rates than controls, 28 and one of the genetic loci robustly associated with schizophrenia 29 is in a gene cluster encoding neuronal nicotinic acetylcholine receptors, which are associated with smoking in the general population

Nicotine is addictive and not risk-free.

It is generally less processed and contains fewer additives than cigarette tobacco, which can be seen as an advantage for some smokers