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In addition, IL-1 and IL-18, markers of inflammasome activation and pyroptosis, were not increased in the macrophage supernatants (Fig

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2022), and phenazopyridine hydrochloride, a novel competitive inhibitor shown to ameliorate Alzheimer's-like phenotypes in mice (Wang et al

The WHO also recommends the use of plant-derived medicines with better safety and therapeutic efficacy in various countries (Palhares et al., 2015)