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Short-term cisplatin exposure induces a ROS-mediated metabolic reprogramming, characterized by PGC-1 activation and increased mitochondrial mass, which can be counteracted by oxidative phosphorylation (OXPHOS) inhibition ( 5 IPF IPF is one of the most difficult respiratory diseases to treat, and its incidence is increasing year by year, primarily in middle-aged and elderly people after the age of 50

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They are as follows: E-Liquids cannot exceed 20mg nicotine strength E-Liquids that contain nicotine must not be sold in bottles larger than 10ml Refillable Vape Tanks/Disposable Vapes must not exceed 2ml total vape juice capacity Product packaging must contain a clear warning that the product may contain nicotine A well as these, Italy also have introduced a taxation on 10ml bottles of e-liquid which has increased year on year since it was introduced in 2021

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The Lancet Global Health, 5 (3), 277-289