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Whether this compositional shift translates to higher lung cancer risk remains unsettled: Conventional observational studies are inconsistent and rarely stratify by potency, but Mendelian randomization (MR) analyses suggest a possible causal signal for lung cancer (and specifically squamous histology) with genetic liability to cannabis use/use disorder (65,66)

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2 In the study led by Williams, researchers recruited a group of teens to buy nicotine e-cigarettes from 98 web-based vendors

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Archived from the original on July 2, 2017