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After that, smuggling declined, probably to less than 5% of sales in 2005.[viii] Incorporating these contraband figures smooths out the 1990s dip in legal sales shown in Figure 1, and it is reasonable to conclude that Italian consumption was fairly steady, at about 2kg per person per annum, throughout the 1980s and 1990s and only really started to decline after about 2000 Smoking and mortality Another way to measure smoking prevalence is via mortality figures as lung cancer rates tend to run about parallel to smoking ones with a lag of 20 years or so

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Even when pneumonia seems to improve on its own, it can leave behind lingering effects if not fully cleared

In line with this, exposure to 10% CSE and 12.5% CSE induced a ~2-3 fold increase protein levels of the anti-oxidant protein Manganese Superoxide Dismutase (Mn-SOD, Figure 3C), a marker of oxidative stress, with a similar increase in Mn-SOD expression upon exposure to 10% CSE and 12.5% CSE at the mRNA level (data not shown)

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