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Other organs were also affected, with the study showing that a pack a day led to an estimated average 97 mutations in each cell in the larynx, 39 mutations for the pharynx, 23 mutations for mouth, 18 mutations for bladder, and six mutations in every cell of the liver each year

The first automatic cigarette rolling machine was invented by James Bonsack in 1880, revolutionizing the industry by allowing mass production of cigarettes

Tobacco, as well as alcohol, can cause mouth, oesophageal and liver cancers

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