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In addition to lung cancer, smoking cigarettes can cause cancers of the throat, mouth, bladder, pancreas, kidneys, and cervix

Flaked tobacco was sometimes stored in a container, the earliest of which were boxes

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Relationships to duration of exposure, smoking, and radiographic abnormalities

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Together, these studies suggest that cigarette smoke targeting the TGF-/Smad signaling pathway induces EMT in COPD