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The RCS models showed a linear negative relationship between TST and trouble sleeping prevalence ( P for total 0.05) and a U-shaped relationship between EST and trouble sleeping prevalence ( P for total and P for nonlinear 0.05), U-shaped relationships of TST and SHBG levels with depression prevalence were shown among males in subgroup analyses (figure S5, P for total and P for nonlinear 0.05)