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An estimated 42.1 million Americans still smoke each year, 18% of men and 15% of women

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The major concerns: We dont have long-term safety data (20+ years) Youth uptake is a massive public health problem Many people end up dual-using (vaping AND smoking) Not FDA-approved for smoking cessation Variable quality and nicotine content between products Cost: $$ - Varies wildly depending on device and liquid Tier 3: Smoking Cessation Methods That Research Shows Probably Don't Work 11

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score

It poses numerous risks and can lead to various serious health issues, not just limited to the mouth

The same bacteria causing periodontal infection can enter your bloodstream, triggering inflammation throughout your body