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EpiAirway were exposed to one puff of either PBS- or WS-23 aerosol, returned to the incubator for 4 h, then exposed to a second puff of PBS- or WS-23 aerosol, after which they recovered in the CO 2 incubator for 24 h

Worldwide, more than 600,000 nonsmokers die each year from exposure to secondhand smoke

Also encouraging continued cigarette use is the desire to avoid cigarette withdrawal symptoms, such as irritability, depressed mood, restlessness, anxiety, and somatic symptoms, which can begin as little as 20 min after smoking but generally peak around 2 h [6, 8]