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This misalignment can cause several issues: Obstruction of Sinus Drainage: When the septum is deviated, it can block the normal flow of mucus from the sinuses to the nasal cavity

John Krystal, Editor of Biological Psychiatry , noted the implications of these findings for developing better ways to help smokers trying to quit

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The bowel may become perforated if the tip of the colonoscope is pushed against the wall of the bowel with too much force, or if the wall of the bowel is injured when a polyp is removed