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Epigenetic mechanisms, such as DNA methylation, RNA methylation, histone modification, exosomes (EXs), and non-coding RNA, with regulatory functions have been continuously revealed [41,42,43]

As a result, dual users may need additional resources and support compared to people who only use one nicotine product

Vaping products, meanwhile, continued to face headwinds

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Advertising for tobacco cigarettes remains banned, as it has been since 1965, but recently the Committee of Advertising Practice ruled e-cigarette vaping which involves inhaling nicotine vapour rather than smoke could appear in advertising under certain conditions