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It also reported that 25% of those with a lifetime history of smoking in the study sample had quit smoking, indicating that people with schizophrenia can overcome tobacco addiction (Krishnadas Reference Krishnadas, Jauhar and Telfer2012)

Similarely, a 6-month exposure of Sprague-Dawley rats to cigarette smoke significant increased ANG II levels and ACE protein expression and decreased ACE2 expression in lung tissue (Yuan et al., 2015)

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