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While there is little research on this specific approach with regard to immunization, health communications theory indicates that such tactics are generalizable.* Development of the Tips campaign was based on formative health communications research, and these types of hard-hitting ads, with real-life health consequences presented in a stark new way, have long been demonstrated to be the most effective

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The quantitative variations in polyphenol substances were either inconclusive (scopoletin) or decreased in all or at least four sample groups of SPL (Fig

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