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Nicotine, the addictive substance in cigarettes, can cause changes in the brain that lead to feelings of pleasure and reward when smoking, which can reinforce the behaviour and create a sense of dependence

Editors note: It is reported today that Pope Francis has banned the sale of cigarettes inside the City State on the grounds that the Holy See cannot profit from a proven health hazard. It is the latest in a long and often surprising history of Catholicism and tobacco, as described by John B

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