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The last thing they need is yet another tax hike that will fall hardest on middle- and lower-income residents

"It threatens to derail a trend that could hasten the demise of cigarettes, poised to take a billion lives this century." Indeed, cigarette smoking is responsible for nearly a half million deaths each year in the U.S

Most relevant to last weeks developments, chain grocery, with its category management practices and tendency to prefer widely distributed products, already presents a formidable challenge for small and independent brewers to get on shelves

Sometimes we simply wind up being responsible for certain things

A pre-specified criterion was established to terminate the trial if the sample size re-estimation indicated that more than 250 participants would need to be randomised in order to detect the expected effect

IBM, Armonk, NY) were used for statistical analysis