Significantly decreased levels of the MoAM associated chemokines CCL2 and CCL7 (21% and 69%, respectively) and a strong trend towards decreased total BALF macrophage counts (30% decrease on average, p = 0.08) in treated animals further corroborates the anti-inflammatory effect of the IRAK4 inhibitor ( Figures 8B, C )
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Insert a flat object, such as a screwdriver from the vehicle tool kit, into the opening and carefully lift off the cover
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