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Shared and specific changes in the smoke-induced T cell immune system To investigate the subpopulation composition, sources, and functional roles of T cells following tobacco smoke exposure, we conducted a comprehensive analysis of the T cell immune system in C57BL/6J mice at early (2 months, 2 M) and later (6 months, 6 M) stages of COPD, alongside an air control (CON) group

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2) and respiration rates (Figs