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Macrophages are also one of the unique components that constitute the lung microenvironment

Banach M, et al

Bernth J, Fldesi D (1992) Sea buckthorn ( Hippophae rhamnoides L.)

Most importantly, growth hormone stimulates the production of insulin-like growth factor-1 (IGF-1), a powerful mediator of tissue growth and repair

Nat Commun (2014) 5:4593

Suppressing Mn-SOD expression or inhibiting AMPK results in the inhibition of this metabolic shift and decreases the survival of transformed cells, highlighting the importance of the Mn-SOD/AMPK pathway in maintaining the bioenergetics of cancer cells, particularly in advanced and aggressive subtypes of breast cancer (Baj et al., 2023[23]